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Nutritional
medicine |
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Cholesterol control alternatives
Lifestyle changes, the right treatment can make a
difference By John
Casey, WEBMD
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Doctors
call it hypercholesterolemia, but most people know
it as plain
old high cholesterol. A
soft, waxy material, cholesterol is a natural part of fats
in the bloodstream and in all the body’s cells.
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Too
much cholesterol circulating in the blood can cause sticky deposits to form
in the artery walls, blocking blood flow.
High cholesterol has no real symptoms, so it can easily
go undetected. The normal range for total blood cholesterol
is less than 200 mg. More than that, and your risk of heart
disease begins to rise.
Given the high-stakes consequences of high
cholesterol — heart attack, stroke — most people
turn to their doctors for the highly effective class of drugs
called statins to lower their cholesterol levels. But there
are many alternative treatments.
“While there are alternative treatments
available, we need to stress that a person’s physician
must be consulted before any of these are started because some
of these can affect prescribed drugs,” says Dr. Roberta
Lee, medical director for the Center for Health and Healing
at the Beth Israel Medical Center in New York.
“People want some kind of magic powder
to sprinkle on their food to lower cholesterol, but the best
alternative treatment is weight loss and eating better, exercise,
and quitting smoking, which will give you the best results
and may allow a person to avoid medications entirely,” says
Dr. Alice H. Lichtenstein, professor of nutrition at Tufts
University and spokeswoman for the American Heart Association.
So, after lifestyle changes to include
regular exercise, which foods and supplements are helpful and
which are full of hype?
Niacin is a B-complex vitamin that at high
doses lowers cholesterol. Doses of 2 to 3 grams per day added
to prescribed statin drugs are a common practice, even among
wholly unalternative doctors. This combination can decrease
cholesterol more than statins can alone and appears to raise
levels of beneficial cholesterol, or HDL. But again, this is
an addition that needs close attention, says Lichtenstein,
because of the potential for serious side effects, including
muscle breakdown, which can lead to frequent muscle pain.
Stanol esters, which are in certain margarines
such as Take Control or Benecol and in pill-form supplements,
are also used in combination with statin drugs. This plant-derived
compound can reduce cholesterol by as much as 10 percent by
stopping the absorption of cholesterol. Again, Less points
out that stanol esters should not be used instead of drugs,
but added to a treatment plan.
What's your Cholesterol IQ?
Soluble fiber is very effective at lowering cholesterol.
Of course, the best way to get fiber is to eat whole grains and vegetables regularly,
but fiber supplements work, too.
How fiber reduces cholesterol is not widely agreed upon,
but it appears that it binds to cholesterol and bile acids in the intestine,
making it unavailable for absorption. Then, when the liver needs to replace the
bile acids that went out with the fiber, it pulls cholesterol from the bloodstream
to make more bile acids. It’s a pretty neat dietary trick.
“Throw in the fact that fiber has all kinds of other
benefits for your entire digestive system, and fiber becomes one of the best
dietary means of lowering cholesterol,” says Lee.
Soy has been the object of attention as an alternative treatment
for a number of ailments, from lowering cholesterol to reducing menopause symptoms.
But Lichtenstein says there is little to support such claims.
“Soy is a great source of low-fat protein,” she
says. “Replace your hamburger with a soy burger. Use it all through your
diet to replace high-fat foods. But the evidence does not support its use in
lowering cholesterol.”
Red yeast rice contains a natural form of the statin drug
Mevacor. Some initial research has shown red yeast rice to be effective in lowering
cholesterol, but according to Lee, the FDA has some issues with it because herbal
doses can vary widely, which is not something you want in cholesterol control.
Garlic is another food that, despite claims to the opposite,
has been shown not to lower cholesterol. A 1998 study in The Journal of the American
Medical Association shows that “consuming garlic does not lower cholesterol,” and
such products cannot be recommended as a way to lower cholesterol.
“Foods like garlic may have many beneficial properties,” says
Lee. “And it may be useful to include those as part of your diet, but that
is different from saying that it can lower cholesterol.”
Coenzyme Q10 is the subject of much debate. It’s credited
with everything from lowering cholesterol to slowing the aging process. But again,
there is not much evidence to support it.
“The data is still very inconclusive on it,” says
Lichtenstein. “None of the reputable health organizations have recommended
it. It’s too early to say whether it will be useful.”
Chromium, lecithin and quercetin and numerous other supplements
are purported to reduce cholesterol, but their use is controversial and should
be used only under the guidance of your doctor.
“What research shows is that 70 percent of patients
are reluctant to share information about alternative therapies they may be taking
with their doctor,” says Lichtenstein. “That’s a real mistake
in general, but especially when it comes to reducing high cholesterol. You need
to let your doctor in on everything you’re taking before you take it.” |
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